購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SOCS2 |
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Immunogen: |
Fusion protein of human SOCS2 |
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Full name: |
suppressor of cytokine signaling 2 |
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Synonyms： |
CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2 |
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SwissProt: |
O14508 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
25-100 |
