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    • 兔抗AKAP12多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW1559
      • 應用 : 僅用于科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱: 兔抗AKAP12多克隆抗體   

    英文名稱:
    Anti-AKAP12 rabbit polyclonal antibody

    別      名: SSeCKS; AKAP250

    相關(guān)類別: 一抗

    儲      存: 冷凍(-20℃)

    宿      主: Rabbit

    抗      原: AKAP12

    反應種屬: Human

    標 記 物: Unconjugate

    克隆類型: rabbit polyclonal

    技術(shù)規(guī)格

    Background:

    The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

    Applications:

    ELISA, WB, IHC

    Name of antibody:

    AKAP12

    Immunogen:

    Synthetic peptide of human AKAP12

    Full name:

    A kinase (PRKA) anchor protein 12

    Synonyms:

    SSeCKS; AKAP250

    SwissProt:

    Q02952

    ELISA Recommended dilution:

    1000-2000

    IHC positive control:

    Human brain and Human ovarian cancer

    IHC Recommend dilution:

    50-200

    WB Predicted band size:

    191 kDa

    WB Positive control:

    HT-29 cells

    WB Recommended dilution:

    200-1000




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