購(gòu)物車
幫助
021-54845833/15800441009
中文名稱：兔抗CASP5多克隆抗體
英文名稱： Anti-CASP5 rabbit polyclonal antibody
別 名： ICH-3; ICEREL-III; ICE(rel)III
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： CASP5
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
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Background: |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CASP5 |
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Immunogen: |
Fusion protein of human CASP5 |
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Full name: |
caspase 5, apoptosis-related cysteine peptidase |
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Synonyms： |
ICH-3; ICEREL-III; ICE(rel)III |
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SwissProt: |
P51878 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human colorectal cancer and human thyroid cancer |
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IHC Recommend dilution: |
25-100 |
