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    • 兔抗SEMA4D多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW20932
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :25ul
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    中文名稱:  兔抗SEMA4D多克隆抗體

    英文名稱: Anti-SEMA4D rabbit polyclonal antibody

    別    名 semaphorin 4D; CD100; SEMAJ; coll-4; C9orf164; M-sema-G

    抗    原: SEMA4D

    儲    存 冷凍(-20℃)

    宿    主 Rabbit

    相關(guān)類別: 一抗

    反應(yīng)種屬 Human, Mouse

    標(biāo) 記 物: Unconjugate

    克隆類型: rabbit polyclonal

    技術(shù)規(guī)格

    Background:

    Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.

    Applications:

    ELISA, IHC

    Name of antibody:

    SEMA4D

    Immunogen:

    Fusion protein of human SEMA4D

    Full name:

    semaphorin 4D

    Synonyms:

    CD100; SEMAJ; coll-4; C9orf164; M-sema-G

    SwissProt:

    Q92854

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human liver cancer

    IHC Recommend dilution:

    50-300



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