購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗WNT1多克隆抗體
英文名稱： Anti-WNT1 rabbit polyclonal antibody
別 名： INT1; OI15; BMND16
相關(guān)類別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： WNT1
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
WNT1 |
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Immunogen: |
Synthetic peptide of human WNT1 |
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Full name: |
wingless-type MMTV integration site family, member 1 |
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Synonyms： |
INT1; OI15; BMND16 |
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SwissProt: |
P04628 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
41 kDa |
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WB Positive control: |
HT-29 cells |
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WB Recommended dilution: |
200-1000 |
