購物車
幫助
021-54845833/15800441009
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Background: |
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. |
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Applications: |
WB |
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Name of antibody: |
FLT3(Phospho-Tyr842) |
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Immunogen: |
Peptide sequence around phosphorylation site of tyrosine 842(S-N-Y(p)-V-V) derived from Human FLT3 . |
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Full name: |
fms-related tyrosine kinase 3 |
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Synonyms： |
FLK2; STK1; CD135; FLK-2 |
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SwissProt: |
P36888 |
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WB Predicted band size: |
113 kDa |
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WB Positive control: |
HepG2 cells lysates treated with EGF |
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WB Recommended dilution: |
500-1000 |
