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    • 兔抗PAK1 (Phospho-Thr212)多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW21207
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱:  兔抗PAK1 (Phospho-Thr212)多克隆抗體


    英文名稱:  Anti-PAK1 (Phospho-Thr212) rabbit polyclonal antibody


    別      名:  PAKalpha


    相關(guān)類別:  一抗


    儲      存:  冷凍(-20℃) 避光


    宿      主:  Rabbit


    抗      原:  PAK1 (Phospho-Thr212)


    反應(yīng)種屬:  Human, Mouse, Rat


    標(biāo)  記  物:  Unconjugate


    克隆類型:  rabbit polyclonal


    技術(shù)規(guī)格

    Background:

    The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

    Applications:

    WB, IHC, IF

    Name of antibody:

    PAK1 (Phospho-Thr212)

    Immunogen:

    Synthetic peptide of human PAK1 (Phospho-Thr212)

    Full name:

    p21 protein (Cdc42/Rac)-activated kinase 1 (Phospho-Thr212)

    Synonyms:

    PAKalpha

    SwissProt:

    Q13153

    IHC positive control:

    Human breast carcinoma

    IHC Recommend dilution:

    50-100

    WB Predicted band size:

    68 kDa

    WB Positive control:

    293 cells untreated or treated with forskolin

    WB Recommended dilution:

    500-1000

    IF Positive control:

    Hela cells

    IF Recommended dilution

    100-200








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