購物車
幫助
021-54845833/15800441009
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Background: |
EFHD2 is a calcium-binding adaptor protein associated with pathologically aggregated tau in Alzheimer disease brain and in a mouse model of frontotemporal dementia. EFHD2 has cell type-specific functions, including modulation of intracellular calcium responses, actin dynamics, and microtubule transport. May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. |
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Applications: |
ELISA, WB |
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Name of antibody: |
EFHD2 |
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Immunogen: |
Synthetic peptide of human EFHD2 |
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Full name: |
EF-hand domain family member D2 |
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Synonyms: |
SWS1 |
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SwissProt: |
Q96C19 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
27 kDa |
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WB Positive control: |
A549 cell lysate |
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WB Recommended dilution: |
200-1000 |
