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021-54845833/15800441009
中文名稱：兔抗CCM2多克隆抗體
英文名稱： Anti-CCM2 rabbit polyclonal antibody
別 名： CCM2 scaffolding protein; OSM; C7orf22; PP10187
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： CCM2
反應種屬： Human
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CCM2 |
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Immunogen: |
Fusion protein of human CCM2 |
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Full name: |
CCM2 scaffolding protein |
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Synonyms: |
OSM; C7orf22; PP10187 |
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SwissProt: |
Q9BSQ5 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human esophagus cancer |
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IHC Recommend dilution: |
20-100 |
