購物車
幫助
021-54845833/15800441009
中文名稱：ALAS1 抗原（重組蛋白）
英文名稱： ALAS1 Antigen (Recombinant Protein)
別 名： aminolevulinate, delta-, synthase 1; ALAS; MIG4; ALAS3; ALASH
儲 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to C terminal 219 amino acids of human ALAS1 |
|
Full name: |
aminolevulinate, delta-, synthase 1 |
|
Synonyms: |
ALAS; MIG4; ALAS3; ALASH |
|
Swissprot: |
P13196 |
|
Gene Accession: |
BC011798 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
