購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗COX7A2L多克隆抗體
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Background: |
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
COX7A2L |
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Immunogen: |
Full length fusion protein |
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Full name: |
cytochrome c oxidase subunit 7A2 like |
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Synonyms: |
EB1; SIG81; COX7AR; COX7RP |
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SwissProt: |
O14548 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
30-150 |
