購物車
幫助
021-54845833/15800441009
中文名稱：CLDND1抗原（重組蛋白）
英文名稱：CLDND1 Antigen (Recombinant Protein)
儲 存：冷凍（-20℃）
相關(guān)類別：抗原
概述
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Fusion protein corresponding to a region derived from 26-140 amino acids of human CLDND1 |
技術(shù)規(guī)格
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Full name: |
claudin domain containing 1 |
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Synonyms: |
C3orf4; GENX-3745 |
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Swissprot: |
Q9NY35 |
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Gene Accession: |
BC001757 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
CLDND1 (claudin domain containing 1), also known as C3orf4 or HSPC174, is a 253 amino acid multi-pass membrane protein that is expressed at high levels in adult brain and at lower levels in adult heart. Existing as two alternatively spliced isoforms, CLDND1 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |
