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    • RRM1抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號 : TW17154
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: RRM1抗原(重組蛋白)

    英文名稱: RRM1 Antigen (Recombinant Protein)

    別       名: R1; RR1; RIR1

    儲       存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to C terminal 226 amino acids of human RRM1

    技術(shù)規(guī)格

    Full name:

    Ribonucleotide reductase M1

    Synonyms:

    R1; RR1; RIR1

    Swissprot:

    P23921

    Gene Accession:

    BC006498

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

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