購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)：BAG1抗原（重組蛋白）
英文名稱(chēng)：BAG1 Antigen (Recombinant Protein)
儲(chǔ) 存：冷凍（-20℃）
相關(guān)類(lèi)別：抗原
概述
|
Fusion protein corresponding to a region derived from 116-345 amino acids of human BAG1 |
技術(shù)規(guī)格
|
Full name: |
BCL2-associated athanogene |
|
Synonyms: |
HAP; BAG-1; RAP46 |
|
Swissprot: |
Q99933 |
|
Gene Accession: |
BC001936 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. |
