購物車
幫助
021-54845833/15800441009
中文名稱：BAD抗原（重組蛋白）
儲 存：冷凍（-20℃）
概述
|
Fusion protein corresponding to a region derived from 15-168 amino acids of human BAD |
技術規(guī)格
|
Full name: |
BCL2-associated agonist of cell death |
|
Synonyms: |
BBC2; BCL2L8 |
|
Swissprot: |
Q92934 |
|
Gene Accession: |
BC001901 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. |
