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    • 兔抗CDK14多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW5570
      • 應(yīng)用 : 僅用于科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱:兔抗CDK14多克隆抗體  

    英文名稱:
    Anti-CDK14 rabbit polyclonal antibody

    別      名: PFTK1; PFTAIRE1

    相關(guān)類別: 一抗

    儲      存:
    冷凍(-20℃)

    宿      主: Rabbit

    抗      原: CDK14

    反應(yīng)種屬: Human, Mouse

    標(biāo) 記 物: Unconjugate

    克隆類型:
    rabbit polyclonal

    技術(shù)規(guī)格

    Background:

    Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.

    Applications:

    ELISA, WB, IHC

    Name of antibody:

    CDK14

    Immunogen:

    Synthetic peptide of human CDK14

    Full name:

    cyclin-dependent kinase 14

    Synonyms:

    PFTK1; PFTAIRE1

    SwissProt:

    O94921

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human liver cancer

    IHC Recommend dilution:

    20-100

    WB Predicted band size:

    53 kDa

    WB Positive control:

    Mouse Pancreas tissue lysate

    WB Recommended dilution:

    200-1000







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