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021-54845833/15800441009
中文名稱：兔抗CARD8多克隆抗體
英文名稱： Anti-CARD8 rabbit polyclonal antibody
別 名： CARD8; CARDINAL; DACAR; DKFZp779L0366; Dakar; FLJ18119; FLJ18121; KIAA0955; MGC57162; NDPP; NDPP1; TUCAN
相關類別： 一抗
抗 原： CARD8
儲 存： 冷凍（-20℃） 避光
宿 主： Rabbit
反應種屬： Human
標 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術規(guī)格
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Background: |
The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. |
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Applications: |
WB |
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Name of antibody: |
CARD8 |
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Immunogen: |
Fusion protein of human CARD8 |
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Full name: |
Caspase recruitment domain-containing protein 8 |
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Synonyms： |
CARD8; CARDINAL; DACAR; DKFZp779L0366; Dakar; FLJ18119; FLJ18121; KIAA0955; MGC57162; NDPP; NDPP1; TUCAN |
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SwissProt: |
Q9Y2G2 |
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WB Predicted band size: |
49 kDa |
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WB Positive control: |
K562 and Hela cells |
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WB Recommended dilution: |
500-2000 |
