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    • 兔抗Bad(Phospho-Ser136)多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW3088
      • 應用 : 僅用于科研使用
      • 貨期 : 現貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱:兔抗Bad(Phospho-Ser136)多克隆抗體   

    英文名稱: Anti-Bad (Phospho-Ser136) rabbit polyclonal antibody

    別      名: Bbc2; AI325008

    相關類別: 一抗

    儲      存: 冷凍(-20℃) 避光

    宿      主: Rabbit

    抗      原: Bad (Phospho-Ser136)

    反應種屬: Human, Mouse, Rat

    標 記 物: Unconjugate

    克隆類型: rabbit polyclonal

    技術規(guī)格

    Background:

    The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.

    Applications:

    WB, IHC

    Name of antibody:

    Bad (Phospho-Ser136)

    Immunogen:

    Synthetic peptide of mouse Bad (Phospho-Ser136)

    Full name:

    BCL2-associated agonist of cell death (Phospho-Ser136)

    Synonyms:

    Bbc2; AI325008

    SwissProt:

    Q61337

    IHC positive control:

    Human breast carcinoma

    IHC Recommend dilution:

    50-100

    WB Predicted band size:

    22 kDa

    WB Positive control:

    HT29 cells untreated or treated with UV

    WB Recommended dilution:

    500-1000





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