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021-54845833/15800441009
中文名稱： 兔抗PSMC4多克隆抗體
英文名稱： Anti-PSMC4 rabbit polyclonal antibody
別 名： S6; RPT3; TBP7; TBP-7; MIP224
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PSMC4
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PSMC4 |
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Immunogen: |
Fusion protein of human PSMC4 |
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Full name: |
proteasome 26S subunit, ATPase 4 |
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Synonyms: |
S6; RPT3; TBP7; TBP-7; MIP224 |
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SwissProt: |
P43686 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human esophagus cancer; |
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IHC Recommend dilution: |
30-150 |
