購物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PPM1M多克隆抗體
英文名稱： Anti-PPM1M rabbit polyclonal antibody
別 名： protein phosphatase, Mg2+/Mn2+ dependent 1M; PP2CE; PP2Ceta; PP2C-eta
相關(guān)類別： 一抗
儲 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： PPM1M
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
|
Background: |
PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42). |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
PPM1M |
|
Immunogen: |
Fusion protein of human PPM1M |
|
Full name: |
protein phosphatase, Mg2+/Mn2+ dependent 1M |
|
Synonyms: |
PP2CE; PP2Ceta; PP2C-eta |
|
SwissProt: |
Q96MI6 |
|
ELISA Recommended dilution: |
5000-10000 |
|
IHC positive control: |
Human liver cancer and Human tonsil |
|
IHC Recommend dilution: |
100-300 |
