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    • 兔抗HDAC5多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW7608
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱: 兔抗HDAC5多克隆抗體

    英文名稱: Anti-HDAC5 rabbit polyclonal antibody

    別      名: HD5; NY-CO-9

    相關(guān)類別: 一抗

    儲      存: 冷凍(-20℃)

    宿      主: Rabbit

    抗      原: HDAC5

    反應(yīng)種屬: Human, Mouse

    標(biāo) 記 物: Unconjugate

    克隆類型: rabbit polyclonal

    技術(shù)規(guī)格

    Background:

    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.

    Applications:

    ELISA, IHC

    Name of antibody:

    HDAC5

    Immunogen:

    Synthetic peptide of human HDAC5

    Full name:

    histone deacetylase 5

    Synonyms:

    HD5; NY-CO-9

    SwissProt:

    Q9UQL6

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human gastric cancer and Human tonsil

    IHC Recommend dilution:

    25-100







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