購物車
幫助
021-54845833/15800441009
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Background: |
Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation (PubMed:29759984). Facilitates Pol II transcription through nucleosomes (PubMed:29759984). Binds DNA (in vitro) (PubMed:29759984). Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3) (PubMed:20850016). Promotes KDM1B demethylase activity (PubMed:23260659). Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300 (PubMed:29759984). Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling (PubMed:16352664). Indirectly promotes phosphorylation of MAPK14 and activation of ATF2 (PubMed:16352664). The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6 (PubMed:16352664). Putative oxidoreductase (PubMed:23260659). |
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Applications: |
ELISA, WB |
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Name of antibody: |
GLYR1 |
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Immunogen: |
Synthetic peptide of human GLYR1 |
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Full name: |
glyoxylate reductase 1 homolog |
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Synonyms: |
NP60; BM045; HIBDL; N-PAC |
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SwissProt: |
Q49A26 |
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ELISA Recommended dilution: |
2000-5000 |
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WB Predicted band size: |
61 kDa |
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WB Positive control: |
Hela, Jurkat, K562 and HUVEC cells |
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WB Recommended dilution: |
500-2000 |
