購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： 兔抗NXF1多克隆抗體
英文名稱(chēng)： Anti-NXF1 rabbit polyclonal antibody
別 名： TAP; MEX67
抗 原： NXF1
儲(chǔ) 存： 冷凍（-20℃） 避光
宿 主： Rabbit
相關(guān)類(lèi)別： 一抗
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： Unconjugate
技術(shù)規(guī)格
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Background: |
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. |
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Applications: |
WB |
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Name of antibody: |
NXF1 |
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Immunogen: |
Synthesized peptide derived from N-terminal of human NXF1. |
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Full name: |
nuclear RNA export factor 1 |
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Synonyms： |
TAP; MEX67 |
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SwissProt: |
Q9UBU9 |
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WB Predicted band size: |
70 kDa |
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WB Positive control: |
HepG2 cells, Jurkat cells and Hela cells lysates |
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WB Recommended dilution: |
500-3000 |
