購(gòu)物車(chē)
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021-54845833/15800441009
中文名稱(chēng)： 兔抗SCN11A多克隆抗體
英文名稱(chēng)： Anti-SCN11A rabbit polyclonal antibody
別 名： NaN; SNS-2; NAV1.9; SCN12A
相關(guān)類(lèi)別： 一抗
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
抗 原： SCN11A
反應(yīng)種屬： Human, Mouse, Rat
標(biāo) 記 物： Unconjugate 、
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SCN11A |
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Immunogen: |
Synthetic peptide of human SCN11A |
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Full name: |
sodium channel, voltage-gated, type XI, alpha subunit |
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Synonyms： |
NaN; SNS-2; NAV1.9; SCN12A |
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SwissProt: |
Q9UI33 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human breast cancer and Human ovarian cancer |
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IHC Recommend dilution: |
50-200 |
