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    • 兔抗MLH3多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW19012
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱:   兔抗MLH3多克隆抗體


    英文名稱:  Anti-MLH3 rabbit polyclonal antibody


    別      名  HNPCC7


    抗     原:  MLH3


    儲      存:  冷凍(-20℃) 避光


    宿      主:  Rabbit


    反應(yīng)種屬:  Human


    相關(guān)類別:  一抗


    標 記  物:  Unconjugate


    克隆類型:  Unconjugate


    技術(shù)規(guī)格

    Background:

    This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

    Applications:

    WB

    Name of antibody:

    MLH3

    Immunogen:

    Synthesized peptide derived from internal of human MLH3.

    Full name:

    mutL homolog 3

    Synonyms:

    HNPCC7

    SwissProt:

    Q9UHC1

    WB Predicted band size:

    164 kDa

    WB Positive control:

    K562 cells and HT29 cells lysates

    WB Recommended dilution:

    500-3000




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