購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： 兔抗MIOX多克隆抗體
英文名稱(chēng)： Anti-MIOX rabbit polyclonal antibody
別 名： ALDRL6
相關(guān)類(lèi)別： 一抗
抗 原： MIOX
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
反應(yīng)種屬： Human
標(biāo) 記 物： Unconjugate
克隆類(lèi)型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
Myo-inositol oxygenase (MIOX), also known as ALDRL6, is a renal-specific member of the Aldo-keto reductase family. It catalyzes the first committed step in the Myo-inositol metabolism pathway and is widely distributed in mammalian tissues. Human Myo-inositol oxygenase shares 91% and 96% sequence homology with mouse and pig Myo-inositol oxygenase homologs, respectively. Myo-inositol oxygenase is responsible for the oxidative cleavage of Myo-inositol (MI) and its epimer D-chiro inositol (DCI) to D-glucuronate. The dioxygen-dependent cleavage of the C1-C6 bond in Myo-inositol is accomplished through the utilization of the Fe(II)/Fe(III) binuclear iron center of MIOX. Myo-inositol oxygenase has also been implicated in complications of diabetes, including diabetic nephropathy. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MIOX |
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Immunogen: |
Full length fusion protein |
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Full name: |
myo-inositol oxygenase |
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Synonyms： |
ALDRL6 |
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SwissProt: |
Q9UGB7 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human brain and Human thyroid cancer |
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IHC Recommend dilution: |
20-100 |
