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    • POT1抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號 : TW18147
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ug
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    中文名稱: POT1抗原(重組蛋白)

    英文名稱: POT1 Antigen (Recombinant Protein)

    別       名: protection of telomeres 1; CMM10; HPOT1

    儲       存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to a region derived from 385-634 amino acids of human POT1

    技術(shù)規(guī)格

    Full name:

    protection of telomeres 1

    Synonyms:

    CMM10; HPOT1

    Swissprot:

    Q9NUX5

    Gene Accession:

    BC002923

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

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