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    • MAP3K12抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW16800
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱(chēng): MAP3K12抗原(重組蛋白)

    英文名稱(chēng): MAP3K12 Antigen (Recombinant Protein)

    別       名: DLK; MUK; ZPK; ZPKP1; MEKK12

    儲(chǔ)       存: 冷凍(-20℃)

    相關(guān)類(lèi)別: 抗原

    概述

    Fusion protein corresponding to a region derived from 125-366 amino acids of human MAP3K12

    技術(shù)規(guī)格

    Full name:

    mitogen-activated protein kinase kinase kinase 12

    Synonyms:

    DLK; MUK; ZPK; ZPKP1; MEKK12

    Swissprot:

    Q12852

    Gene Accession:

    BC050050

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.

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