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    • 兔抗DENND1B多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW18118
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱(chēng):兔抗DENND1B多克隆抗體  

    英文名稱(chēng): Anti-DENND1B rabbit polyclonal antibody

    別      名: DENN domain containing 1B; FAM31B; C1ORF18; C1orf218

    相關(guān)類(lèi)別: 一抗

    儲(chǔ)      存: 冷凍(-20℃)

    宿      主: Rabbit

    抗      原: DENND1B

    反應(yīng)種屬: Human, Mouse

    標(biāo)  記 物: Unconjugate

    克隆類(lèi)型: rabbit polyclonal

    技術(shù)規(guī)格

    Background:

    Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery.

    Applications:

    ELISA, WB

    Name of antibody:

    DENND1B

    Immunogen:

    Fusion protein of human DENND1B

    Full name:

    DENN domain containing 1B

    Synonyms:

    FAM31B; C1ORF18; C1orf218

    SwissProt:

    Q6P3S1

    ELISA Recommended dilution:

    5000-10000

    WB Predicted band size:

    86 kDa

    WB Positive control:

    Human fetal brain tissue and mouse brain tissue lysates

    WB Recommended dilution:

    500-2000



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