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    • 兔抗NPHS1多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW20941
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱:  兔抗NPHS1多克隆抗體


    英文名稱:  Anti-NPHS1 rabbit polyclonal antibody


    別       名:  CNF; NPHN; nephrin


    相關(guān)類別:  一抗


    抗       原:  NPHS1


    儲       存:  冷凍(-20℃)


    宿       主:  Rabbit


    反應(yīng)種屬:  Human

    標(biāo)  記  物:  Unconjugate


    克隆類型:  rabbit polyclonal


    技術(shù)規(guī)格

    Background:

    This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.

    Applications:

    ELISA, IHC

    Name of antibody:

    NPHS1

    Immunogen:

    Synthetic peptide of human NPHS1

    Full name:

    nephrosis 1, congenital, Finnish type (nephrin)

    Synonyms:

    CNF; NPHN; nephrin

    SwissProt:

    O60500

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human lung cancer

    IHC Recommend dilution:

    25-100





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