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    • SOCS2抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號 : TW17207
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: SOCS2抗原(重組蛋白)

    英文名稱: SOCS2 Antigen (Recombinant Protein)

    別       名: CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2

    儲       存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to a region derived from 31-198 amino acids of human SOCS2

    技術(shù)規(guī)格

    Full name:

    suppressor of cytokine signaling 2

    Synonyms:

    CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2

    Swissprot:

    O14508

    Gene Accession:

    BC010399

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor.

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