購物車
幫助
021-54845833/15800441009
中文名稱：ACLY抗原（重組蛋白）
英文名稱： ACLY Antigen (Recombinant Protein)
別 名： ACL; ATPCL; CLATP
儲 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human ACLY |
|
Full name: |
ATP citrate lyase |
|
Synonyms: |
ACL; ATPCL; CLATP |
|
Swissprot: |
P53396 |
|
Gene Accession: |
BC006195 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. |
