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    • CABLES1抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW16846
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱:  CABLES1抗原(重組蛋白)

    英文名稱: CABLES1 Antigen (Recombinant Protein)

    別      名: CABL1; IK3-1; CABLES; HsT2563

    儲(chǔ)      存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概  述:

    Fusion protein corresponding to C terminal 250 amino acids of human CABLES1


    技術(shù)規(guī)格: 

    Full name:

    Cdk5 and Abl enzyme substrate 1

    Synonyms:

    CABL1; IK3-1; CABLES; HsT2563

    Swissprot:

    Q8TDN4

    Gene Accession:

    BC037218

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene.

     

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