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    • LAT2抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號 : TW16758
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: LAT2抗原(重組蛋白)

    英文名稱: LAT2 Antigen (Recombinant Protein)

    別       名: LAB, NTAL, WSCR5, WBSCR5, HSPC046, WBSCR15

    儲       存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to a region derived from 27-243 amino acids of human LAT2

    技術(shù)規(guī)格

    Full name:

    linker for activation of T cells family, member 2

    Synonyms:

    LAB, NTAL, WSCR5, WBSCR5, HSPC046, WBSCR15

    Swissprot:

    Q9GZY6

    Gene Accession:

    BC001609

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

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