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    • MCM3抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW16824
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1ml/100ug
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    中文名稱: MCM3抗原(重組蛋白)

    英文名稱: MCM3 Antigen (Recombinant Protein)

    別       名: HCC5, P1.h, RLFB, P1-MCM3

    儲(chǔ)       存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述

    Fusion protein corresponding to C terminal 300 amino acids of human MCM3

    技術(shù)規(guī)格

    Full name:

    minichromosome maintenance complex component 3

    Synonyms:

    HCC5, P1.h, RLFB, P1-MCM3

    Swissprot:

    P25205

    Gene Accession:

    BC001626

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

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