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    • MEIOB抗原(重組蛋白)

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      • 品牌 : 通蔚生物
      • 目錄號 : TW17377
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :1mg/100ug
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    中文名稱: MEIOB 抗原(重組蛋白)

    英文名稱: MEIOB Antigen (Recombinant Protein)

    別      名: meiosis specific with OB domains; gs129; C16orf73

    儲      存: 冷凍(-20℃)

    相關(guān)類別: 抗原

    概述


    Fusion protein corresponding to a region derived from 245-442 amino acids of human MEIOB

    技術(shù)規(guī)格

    Full name:

    meiosis specific with OB domains

    Synonyms:

    gs129; C16orf73

    Swissprot:

    Q8N635

    Gene Accession:

    BC029829

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro (By similarity).

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