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021-54845833/15800441009
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Background: |
May act as the primary docking protein directing membrane turnover and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
SESTD1 |
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Immunogen: |
Fusion protein of human SESTD1 |
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Full name: |
SEC14 and spectrin domains 1 (SESTD1) |
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Synonyms: |
SOLO |
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SwissProt: |
Q86VW0 |
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IHC positive control: |
adenocarcinoma of human colon tissue and carcinoma of human lung tissue; adenocarcinoma of human ovary tissue and adenocarcinoma of human endometrium tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
79 kDa |
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WB Positive control: |
HepG2, Hela, SVT2, Jurkat cell lysates |
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WB Recommended dilution: |
200-1000 |
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