購(gòu)物車
幫助
021-54845833/15800441009
中文名稱： 兔抗PSMD8多克隆抗體
英文名稱： Anti-PSMD8 rabbit polyclonal antibody
別 名： S14, p31, HIP6, HYPF, Nin1p, Rpn12
儲(chǔ) 存： 冷凍（-20℃）
宿 主： Rabbit
相關(guān)類別： 一抗
反應(yīng)種屬： Human, Mouse
標(biāo) 記 物： Unconjugate
克隆類型： rabbit polyclonal
技術(shù)規(guī)格
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Background: |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PSMD8 |
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Immunogen: |
Fusion protein of human PSMD8 |
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Full name: |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 |
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Synonyms： |
S14, p31, HIP6, HYPF, Nin1p, Rpn12 |
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SwissProt: |
P48556 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human colon cancer and human lung cancer |
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IHC Recommend dilution: |
50-200 |
