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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW1100
      • 應(yīng)用 : 僅用于科研使用
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    中文名稱: 兔抗ACTN1多克隆抗體

    英文名稱: Anti-ACTN1 rabbit polyclonal antibody

    別      名: BDPLT15

    抗      原: ACTN1

    儲(chǔ)      存: 冷凍(-20℃)

    宿      主: Rabbit

    相關(guān)類別: 一抗

    反應(yīng)種屬: Human, Mouse, Rat

    標(biāo) 記 物: Unconjugate

    克隆類型: rabbit polyclonal

    技術(shù)規(guī)格

    Background:

    Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

    Applications:

    ELISA, WB

    Name of antibody:

    ACTN1

    Immunogen:

    Fusion protein of human ACTN1

    Full name:

    actinin, alpha 1

    Synonyms:

    BDPLT15

    SwissProt:

    P12814

    ELISA Recommended dilution:

    500-1000

    WB Predicted band size:

    103/106 kDa

    WB Positive control:

    231,A549 and Hela cell lysates

    WB Recommended dilution:

    200-1000


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