購物車
幫助
021-54845833/15800441009
技術(shù)規(guī)格
|
Background: |
The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
ITGB2 |
|
Immunogen: |
Fusion protein of human ITGB2 |
|
Full name: |
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
|
Synonyms： |
LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1 |
|
SwissProt: |
P05107 |
|
ELISA Recommended dilution: |
1000-2000 |
|
IHC positive control: |
Human brain |
|
IHC Recommend dilution: |
25-100 |
