購物車
幫助
021-54845833/15800441009
中文名稱：CBX5抗原（重組蛋白）
英文名稱：CBX5 Antigen (Recombinant Protein)
儲 存：冷凍（-20℃）
相關類別：抗原
概述
|
Fusion protein corresponding to a region derived from 1-191 amino acids of human CBX5 |
技術規(guī)格
|
Full name: |
chromobox 5 |
|
Synonyms: |
HP1; HP1A; HEL25 |
|
Swissprot: |
P45973 |
|
Gene Accession: |
BC006821 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
