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021-54845833/15800441009
中文名稱：BCL2L2抗原（重組蛋白）
英文名稱：BCL2L2 Antigen (Recombinant Protein)
儲 存：冷凍（-20℃）
相關(guān)類別：抗原
概述
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Fusion protein corresponding to a region derived from 1-188 amino acids of human BCL2L2 |
技術(shù)規(guī)格
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Full name: |
BCL2-like 2 |
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Synonyms: |
BCLW; BCL-W; PPP1R51; BCL2-L-2 |
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Swissprot: |
Q92843 |
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Gene Accession: |
BC113522 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. |
