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    • 兔抗CERS6多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW5978
      • 應用 : 僅用于科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱:兔抗CERS6多克隆抗體

    英文名稱:
    Anti-CERS6 rabbit polyclonal antibody

    別      名: CERS5; LASS6

    相關(guān)類別: 一抗

    儲      存: 冷凍(-20℃)

    宿      主: Rabbit

    抗      原: CERS6

    反應種屬: Human, Mouse

    標 記 物: Unconjugate

    克隆類型:
    rabbit polyclonal

    技術(shù)規(guī)格

    Background:

    The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they all are involved in sphingolipid synthesis. LASS6 is a widely expressed 384 amino acid endoplasmic reticulum, multi-pass membrane protein. On the luminal side of the endoplasmic reticulum membrane, the N-terminal asparagine residue is glycosylated. In cells deficient for CLN9, LASS6 corrects growth and apoptosis, and increases the levels of short ceramide species, such as C14:0- and C16:0-ceramides.

    Applications:

    ELISA, IHC

    Name of antibody:

    CERS6

    Immunogen:

    Synthetic peptide of human CERS6

    Full name:

    ceramide synthase 6

    Synonyms:

    CERS5; LASS6

    SwissProt:

    Q6ZMG9

    ELISA Recommended dilution:

    2000-5000

    IHC positive control:

    Human ovarian cancer and Human brain

    IHC Recommend dilution:

    50-200




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