購(gòu)物車(chē)
幫助
021-54845833/15800441009
中文名稱(chēng)： TYK2 抗原（重組蛋白）
英文名稱(chēng)： TYK2 Antigen (Recombinant Protein)
別 名： tyrosine kinase 2; JTK1; IMD35
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類(lèi)別：抗原
概 述
|
Full name: |
tyrosine kinase 2 |
|
Synonyms: |
JTK1; IMD35 |
|
Swissprot: |
P29597 |
|
Gene Accession: |
BC014243 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. |
