購(gòu)物車(chē)
幫助
021-54845833/15800441009
|
Background: |
Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1. |
|
Applications: |
ELISA, WB |
|
Name of antibody: |
ZFP42 |
|
Immunogen: |
Synthetic peptide of human ZFP42 |
|
Full name: |
ZFP42 zinc finger protein |
|
Synonyms： |
REX1; ZNF754 |
|
SwissProt: |
Q96MM3 |
|
ELISA Recommended dilution: |
1000-2000 |
|
WB Predicted band size: |
35 kDa |
|
WB Positive control: |
A549, K562 and PC3 cells |
|
WB Recommended dilution: |
200-1000 |
