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    • 兔抗WEE2多克隆抗體

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      • 品牌 : 通蔚生物
      • 目錄號 : TW4475
      • 應用 : 僅限于科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱: 兔抗WEE2多克隆抗體

    英文名稱:
    Anti-WEE2 rabbit polyclonal antibody

    別       名:
    WEE1B

    相關類別:一抗

    儲       存:
    冷凍(-20℃)

    宿       主:
    Rabbit

    抗       原:
    WEE2

    反應種屬:
    Human

    標 記  物:
    Unconjugate

    克隆類型:
    rabbit polyclonal

    技術規(guī)格

    Background:

    Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1/CDC2 and acts as a key regulator of meiosis during both prophase I and metaphase II (PubMed:29606300). Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).

    Applications:

    ELISA, IHC

    Name of antibody:

    WEE2

    Immunogen:

    Synthetic peptide of human WEE2

    Full name:

    WEE1 homolog 2

    Synonyms:

    OOMD5; WEE1B

    SwissProt:

    P0C1S8

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human liver cancer and Human colorectal cancer

    IHC Recommend dilution:

    25-100



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