購物車
幫助
021-54845833/15800441009
中文名稱：兔抗BAGE2多克隆抗體
|
Background: |
Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22% of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis. |
|
Applications: |
ELISA, WB, IHC |
|
Name of antibody: |
BAGE2 |
|
Immunogen: |
Synthetic peptide of human BAGE2 |
|
Full name: |
B melanoma antigen family member 2 |
|
Synonyms: |
CT2.2 |
|
SwissProt: |
Q86Y30 |
|
ELISA Recommended dilution: |
5000-10000 |
|
IHC positive control: |
Human liver cancer |
|
IHC Recommend dilution: |
25-100 |
|
WB Predicted band size: |
12 kDa |
|
WB Positive control: |
A375 cell lysate |
|
WB Recommended dilution: |
200-1000 |
