購(gòu)物車
幫助
021-54845833/15800441009
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Background: |
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. |
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Applications: |
WB |
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Name of antibody: |
TFE3 |
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Immunogen: |
Synthetic peptide of human TFE3 |
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Full name: |
transcription factor binding to IGHM enhancer 3 |
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Synonyms： |
TFEA; RCCP2; RCCX1; bHLHe33 |
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SwissProt: |
P19532 |
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WB Predicted band size: |
62 kDa |
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WB Positive control: |
293 cells |
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WB Recommended dilution: |
500-1000 |
