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      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW21003
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱兔抗SERPINB5多克隆抗體   

    英文名稱: Anti-SERPINB5 rabbit polyclonal antibody

    別      名 PI5, maspin

    抗      原: SERPINB5

    儲(chǔ)      存: 冷凍(-20℃)

    宿      主: Rabbit

    相關(guān)類別: 一抗

    反應(yīng)種屬: Human, Mouse

    標(biāo)記物 Unconjugate

    克隆類型 rabbit polyclonal

    技術(shù)規(guī)格

    Background:

    Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor.It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

    Applications:

    ELISA, WB, IHC

    Name of antibody:

    SERPINB5

    Immunogen:

    Fusion protein of human SERPINB5

    Full name:

    serpin peptidase inhibitor, clade B (ovalbumin), member 5

    Synonyms:

    PI5, maspin

    SwissProt:

    P36952

    ELISA Recommended dilution:

    2000-10000

    IHC positive control:

    Human esophagus cancer and human lung cancer

    IHC Recommend dilution:

    100-300

    WB Predicted band size:

    42 kDa

    WB Positive control:

    Mouse esophagus and human cervical cancer tissue

    WB Recommended dilution:

    1000-5000




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