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    • 兔抗NR1H3多克隆抗體

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      價(jià)格:
      • 品牌 : 通蔚生物
      • 目錄號(hào) : TW20973
      • 應(yīng)用 : 僅供科研使用
      • 貨期 : 現(xiàn)貨
      • 規(guī)格 :100ul/200ul/25ul
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    中文名稱: 兔抗NR1H3多克隆抗體


    英文名稱: Anti-NR1H3 rabbit polyclonal antibody


    別      名: LXR-a; LXRA; RLD-1


    相關(guān)類別: 一抗


    儲(chǔ)      存: 冷凍(-20℃) 避光


    宿     主: Rabbit


    抗     原: NR1H3


    反應(yīng)種屬: Human, Mouse, Rat


    標(biāo)  記  物: Unconjugate


    克隆類型: rabbit polyclonal


    技術(shù)規(guī)格

    Background:

    The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Applications:

    WB

    Name of antibody:

    NR1H3

    Immunogen:

    Fusion protein of human NR1H3

    Full name:

    nuclear receptor subfamily 1, group H, member 3

    Synonyms:

    LXR-a; LXRA; RLD-1

    SwissProt:

    Q13133

    WB Predicted band size:

    50 kDa

    WB Positive control:

    MCF7 cells

    WB Recommended dilution:

    500-2000




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